The Nanocrine Plasmonic Imaging Lab, as part of Nanocrine, provides microscope-based plasmonic imaging and analysis services to academic laboratories, biopharma, and research institutions. Our scientists are equipped with state-of-the-art Zeiss and Ocean Optics equipment at our company in Frederick, Maryland.

• Plasmonic Imaging – Compatible with single-cell, co-culture, and tissue. Multi-sensor location capture coupled with timelapse imagery provides spatio-kinetic profiling of molecules as they are released from living cells. Cell imagery is captured concurrently.


• Data Analysis – Every project is unique. Work with our scientists to determine the level of analysis you need. Raw data to advanced analysis is available.


• Collaborative Effort – Our expertise in plasmonic imaging is leveraged for successful experiments. Get in touch with us.

All projects start with a detailed discussion to fully understand the scope of the project. You will work with our scientists to correctly identify an optimal approach that yields actionable data for follow on experiments or publication.

We carry some of the most commonly used cell lines for life science R&D that our clients may choose from for their experiment. Alternatively, ship your samples to our facility using the instructions provided on our website (insert link). Monoculture cells, cocultures, spheroids, organoids, and tissue are compatible with plasmonic imaging.

In addition to pre-validated nanosensor design, we provide data demonstrating the Plasmonic Imaging Biochip functional capacity for quantifiably detecting client-selected targets in a cell-free environment. We carefully select and use optimized chemistries and nanostructure geometries for optimized signal.

The format of the experiment is guided by the goal of our clients. We have the capability to detect with spatial resolution target analytes as they are secreted by living cells. We have validated geometries for the plasmonic sensor arrays as well as binding partners. On request, we can accommodate custom geometries and novel binding partners.

• High-Resolution Images - Clear images of cells and plasmonic nanostructure arrays.


• Analysis Reports - Comprehensive analysis on plasmonic response, cell morphology, and client-selected fluorescence biomarker characterization.


• Data Files - All raw and processed data files.


• Professional Consultation - Expert interpretations and guidance.

To better understand how plasmonic imaging can open new avenues of scientific inquiry for you or your group, or to answer questions that have not been directly approachable, please contact us to discuss your project with our team of experts.