Real-Time Single-Cell Protein Secretion Imaging
A plasmonic imaging method for real-time spatial profiling of extracellular signaling molecules during live-cell timelapse microscopy using light microscopes
We are pleased to announce our poster has been accepted for publication at ASCB 2025.
The ability to directly observe cell-secreted proteins with spatial resolution has long been a barrier in cell biology and disease research. Conventional assays such as ELISA quantify secreted factors only in bulk, obscuring heterogeneity and preventing insight into how individual cells contribute to their microenvironment.
In this poster, we present a nanoplasmonic imaging platform that enables real-time, label-free detection of secreted proteins with spatial resolution compatible with live-cell microscopy on standard light microscopes.
